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Dental Sealant Toxicity

Dr. Omar M. Amin, Ph.D.

Neurocutaneous Syndrome (NCS), a dermatological and neurological disorder

Abstract: Neurocutaneous syndrome (NCS), a newly discovered toxicity disorder, is described in light of our new understanding of its relationships with the causative agents included in the dental liners used in afflicted patients. NCS is characterized by neurological sensations, pain, depleted energy and memory loss as well as itchy cutaneous lesions that may invite various opportunistic infections. Components in the calcium hydroxide dental sealants Dycal, Life and Sealapex have been identified as sources of the observed symptoms considered compatible with classical sulfa toxicity. Sulfonamide and neurological toxicity issues are discussed, three case histories are presented and an outline of management protocol is proposed. Additional notes on zinc oxide, Fynal, IRM and Sultan U/P sealants are also included.

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